BURUN SEPTUMINING TO‘SIG‘INING RIVOJLANISHI VA KECHISHIDA IRSIY OMILLARNING ROLI

Norjigitov Firdavs Nodirjonovich; Ubaydullayev Muhammadjon Karim o‘g‘li; Boqiyev Jahongir Nodirjon o'g'li

Authors

Norjigitov Firdavs Nodirjonovich Toshkent Tibbiyot Akademiyasi Otolaringologiya kafedrasi assistenti.
Ubaydullayev Muhammadjon Karim o‘g‘li Toshkent Tibbiyot Akademiyasi talabasi.
Boqiyev Jahongir Nodirjon o'g'li Toshkent tibbiyot akademiyasi talabasi

Keywords:

Kraniofasiyal, rivojlanish, frontonazal, genetika, asab hujayralari hujayrasi, burun

Abstract

Burun yuz estetikasini aniqlashda markaziy hisoblanadi. Uning tarkibiy xususiyatlarining o'zgarishi ortodontik terapiya oxirida dentoskeletal joylashuviga katta ta'sir ko'rsatadi. Uning rivojlanish etiologiyasiga ehtiyotkorlik bilan qarash bemorning yuz qiyofasi haqida haqiqiy tashvishini aniqlashda sog'liqni saqlash mutaxassisiga katta yordam beradi. Bu, o'z navbatida, bo'shliqning barc1ha uch o'lchovida tishlar va jag'larni joylashtirish maqsadlari bo'yicha yaxshiroq davolash rejasini tuzishga yordam beradi. Biroq, ushbu muhim tuzilma ko'pincha ortodontistlar tomonidan uning rivojlanish etiologiyasini sinchkovlik bilan tushunmaganligi sababli diagnostika va davolashni rejalashtirish rejimining bir qismi sifatida o'tkazib yuboriladi.

References

Pan A, Chang L, Nguyen A, James AW. A review of hedgehog signaling in cranial bone development. Front Physiol. 2013;4:61. doi: 10.3389/fphys.2013.00061. [DOI] [PMC free article] [PubMed] [Google Scholar]

Takimoto A, Mohri H, Kokubu C, Hiraki Y, Shukunami C. Pax1 acts as a negative regulator of chondrocyte maturation. Exp Cell Res. 2013;319:3128–39. doi: 10.1016/j.yexcr.2013.09.015. [DOI] [PubMed] [Google Scholar]

Pius S, Ibrahim HA, Bello M, Mbaya K, Ambe JP. Apert syndrome: A case report and review of literature. Open J Pediatr. 2016;6:175–84. [Google Scholar]

Szeremeta W, Parikh TD, Widelitz JS. Congenital nasal malformations. Otolaryngol Clin North Am. 2007;40:97–112. doi: 10.1016/j.otc.2006.10.008. [DOI] [PubMed] [Google Scholar]

Patil S, Rao RS, Majumdar B. Single gene disorders with craniofacial and oral manifestations. J Contemp Dent Pract. 2024;15:659–71. doi: 10.5005/jp-journals-10024-1596. [DOI] [PubMed] [Google Scholar]

Pingault V, Ente D, Dastot-Le Moal F, Goossens M, Marlin S, Bondurand N. Review and update of mutations causing Waardenburg syndrome. Hum Mutat. 2020;31:391–406. doi: 10.1002/humu.21211. [DOI] [PubMed] [Google Scholar]