THE IMPORTANCE OF ENDOTHELIAL DYSFUNCTION IN THE DEVELOPMENT OF DISORDERS OF THE HEMOSTASIS SYSTEM IN PATIENTS WITH RHEUMATOID ARTHRITIS

Authors

  • Musaeva Nargiza Bakhtiyorovna Department of Hematology, Transfusiology and Laboratory Science Tashkent Medical Academy

Keywords:

blood coagulation system, venous thromboembolism, inflammation, rheumatoid arthritis, thrombosis, blood clotting factors, complement, cytokines.

Abstract

The article contains information about the physiology of the hemostatic system and its components, and discusses the connection between the hemostatic system and inflammation. The physiology of normal hemostasis, the interaction of platelets with endothelial cells and leukocytes, as well as with von Willebrand factor and the complement system and their role in rheumatoid arthritis are described.

References

Reshetnyak VI, Zhuravel SV, Kuznetsova NK, Pisarev VM, Klychnikova EV, Syutkin VE, Reshetnyak TM. The hemostasis system is normal and during liver transplantation (review). General resuscitation. 2018;(5):85-96.

Strukova SM. Fundamentals of physiology of hemostasis. 2nd ed. Moscow: Moscow State University Publishing House; 2013. Strukova SM. Osnovy fiziologii gemostaza

Aksu K, Donmez A, Keser G. Inflammation-Induced Thrombosis: Mechanisms, Disease Associations and Management. Curr Pharm Des. 2012;18(11): 1478-93.

Levi M, van der Poll T, Buller HR. Bidirectional relation between inflammation and coagulation. Circulation. 2014 Jun 8; 109(22):2698-704. doi: 10.1161/01.CIR. 0000131660.51520.9A.

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Published

2024-01-07

Issue

Vol. 3 No. 1 (2023): ICSRNSS

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

THE IMPORTANCE OF ENDOTHELIAL DYSFUNCTION IN THE DEVELOPMENT OF DISORDERS OF THE HEMOSTASIS SYSTEM IN PATIENTS WITH RHEUMATOID ARTHRITIS. (2024). Proceedings of International Conference on Scientific Research in Natural and Social Sciences, 3(1), 163-166. https://econferenceseries.com/index.php/srnss/article/view/3534