MET235THR POLYMORPHISM IN THE AGT GENE IN THE DEVELOPMENT OF CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WHO HAVE HAD COVID-19 IN THE UZBEK POPULATION
Abstract
During the COVID-19 pandemic, many large studies have confirmed a direct relationship between the severity of the infectious disease and a history of diabetes mellitus. According to the observations of Chinese scientists, the majority of deaths were observed among patients with comorbid pathologies, including hypertension (53.8%), diabetes (42.3%), heart disease (19.2%) and strokes (15.4%). In Italy, the sickest patients requiring treatment in the intensive care unit often had hypertension (49%), other cardiovascular diseases (21%) and diabetes (17%). The severe course of Covid-19 in patients with diabetes mellitus against the background of cardiovascular pathology is associated with the development of endothelial dysfunction, which prompted us to begin our own research in this area.
References
Angelidi A.M., Belanger M.J., Mantzoros C.S. COVID-19 and diabetes mellitus: what we know, how our patients should be treated now, and what should happen next. Metabolism 2020; 107: 154245, https://doi.org/10.1016/ 2. Deng S.Q., Peng
H.J. Characteristics of and public health responses to the coronavirus disease 2019 outbreak in China. J Clin Med 2020; 9(2): 575, https://doi.org/10.3390/ jcm9020575.
Diaz J.H. Hypothesis: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19. J Trav Med 2020; 27(3): taaa041,https://doi.org/10.1093/jtm/ taaa041.
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