MOLECULAR GENETIC ANALYSIS OF COX2 GENE POLYMORPHISM IN CHRONIC POLYPOSIS RHINOSINUSITIS

Ilyosjon O. Soatov; Jamolbek A. Djuraev

Authors

Ilyosjon O. Soatov Tashkent Medical Academy, Researcher, Tashkent, Uzbekistan
Jamolbek A. Djuraev Tashkent Medical Academy, Doctor of Medical Sciences (DSc), Tashkent, Uzbekistan

Keywords:

Polymorphism, encoded gene, inflammatory response, COX2 gene, homozygous.

Abstract

Analysis of the contribution of the COX2 gene polymorphism to the frequency of occurrence, development and clinical course. The prevalence of the rs20417 76 G/C polymorphism in the COX2 gene was analyzed among patients with chronic polyposis rhinosinusitis and chronic rhinosinusitis and in the control group. We can conclude that there are no significant differences in the frequency of detection of allelic and genotypic variants of the 76 G/C polymorphic locus in the COX2 gene.

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