THE ROLE OF NEBULIZER USE OF ACETYLCYSTEINE IN THE TREATMENT OF RECURRENT OBSTRUCTIVE BRONCHITIS IN CHILDREN

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Lim Maxim Vyacheslavovich
Khaydarov Odilkhon Lazizovich

Abstract

Recurrent obstructive bronchitis is a pathological condition with recurring episodes of bronchial obstruction against the background of acute respiratory infections. The aim of the study was to investigate the role of 10% acetylcysteine nebulizer in the treatment of recurrent obstructive bronchitis in children. The use of nebulizer inhalations with acetylcysteine led to a significant (P<0.05; P<0.01) reduction in the duration of oxygen therapy, a reduction in inpatient treatment of patients by an average of 0.3 and 0.9 days in patients of group II compared with patients who received standard therapy for the disease. Thus, the use of nebulizer inhalations of a 10% solution of acetylcysteine in recurrent obstructive bronchitis in children helps to reduce the intensity and duration of cough, sputum viscosity, leads to a significant decrease in the severity of bronchial obstruction according to E:I index. The use of the drug causes a decrease in the duration of oxygen therapy and the duration of inpatient treatment, which makes it possible to recommend the use of this method in the treatment of the disease.

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How to Cite
Lim Maxim Vyacheslavovich, & Khaydarov Odilkhon Lazizovich. (2023). THE ROLE OF NEBULIZER USE OF ACETYLCYSTEINE IN THE TREATMENT OF RECURRENT OBSTRUCTIVE BRONCHITIS IN CHILDREN. Proceedings of International Conference on Modern Science and Scientific Studies, 2(6), 74–82. Retrieved from https://econferenceseries.com/index.php/icmsss/article/view/2247
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References

Batagov S.Ya.Acetylcysteine in the treatment of lower respiratory tract infections in adults. Attending doctor. 2014.-N 10.-S.68-71.

Geppe N.A., Seliverstova N.A., Malyshev V.S., Mashukova N.G., Kolosova N.G. Causes of bronchial obstruction in children and directions of therapy // RMJ. 2011. No. 22.

Davydova I.V., Turti T.V., Baranova L.S. Experience in the use of acetylcysteine in the treatment of respiratory infections in young children // Pediatric pharmacology. 2012. No. 9 (2). pp. 67-72

Ushkalova E.A. Acetylcysteine in clinical practice: present and prospects // Farmateka. 2007. No. 17. S. 30-36.

Shavazi N. M., Lim M. V., Rustamov M. R., Gaibullaev Zh. Sh., Lim V. I. Evaluation of the effectiveness of new methods of therapy for recurrent obstructive bronchitis. Achievements in science and education, 2020, 10(64), 80-82.

Shavazi N. M., Rustamov M. R., Lim M. V., E: I INDEX-Method for objective assessment of bronchial obstructive syndrome in children //Academy. – 2019. – no. 10 (49). - S. 44-49.

Shavazi N.M., Lim M.V., Zakirova B.I., Lim V.I., Tursunkulova D.A. Assessment of the degree of bronchial obstruction in acute bronchiolitis in young children. Materials of the III Congress of the Association of Doctors of Emergency Medical Care of Uzbekistan. Tashkent, October 29-30, 2015, p. 285.

Duijvestijn YCM, Mourdi N. Smuchny J. et al. Acetylcysteine and carbocysteine for acute upper and low respiratory tract infections in pediatric patients without chronic broncho pulmonary disease (Review) // Cochrane Database Syst. Rev. 2010 Vol. 9. P. 1-22.