РЕЦИДИВИРУЮЩИЙ БРОНХИТ У ДЕТЕЙ
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Abstract
Хронический кашель определяется как ежедневный кашель, сохраняющийся более 4 недель. Затяжной бактериальный бронхит (ЗББ) является частой причиной хронического влажного кашля у детей дошкольного возраста без симптомов или признаков других специфических причин, и его разрешение обычно наступает после 2-недельного курса соответствующего перорального антибиотика. Диагноз в основном клинический; как правило, инструментальные исследования не требуются.
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References
Kantar A, Chang AB, Shields MD, Marchant JM, Grimwood K, Grigg J, et al.. ERS statement on protracted bacterial bronchitis in children. Eur Respir J. (2017) 50:1602139. 10.1183/13993003.02139-2016
Chang AB, Glomb WB. Guidelines for evaluating chronic cough in pediatrics. Chest. (2006) 129:260S−83S. 10.1378/chest.129.1_suppl.260S
Chang AB, Oppenheimer JJ, Weinberger MM, Rubin BK, Grant CC, Weir K, et al.. Management of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and expert panel report. Chest. (2017) 151:884–90. 10.1016/j.chest.2017.01.025
Morice AH, Millqvist E, Bieksiene K, Birring SS, Dicpinigaitis P, Ribas CD, et al.. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. (2020) 55:1901136. 10.1183/13993003.01136-2019
Shields MD, Bush A, Everard ML, McKenzie S, Primhak R. Recommendations for the assessment and management of cough in children. Thorax. (2008) 63(Suppl. 3):1–16. 10.1136/thx.2007.077370
Newcombe PA, Sheffield JK, Chang AB. Minimally important change in a parent-proxy quality-of-life questionnaire for pediatric chronic cough. Chest. (2011) 139:576–80. 10.1378/chest.10-1476
Kantar A. Update on pediatric cough. Lung. (2016) 194:9–14. 10.1007/s00408-015-9815-6
Chang AB, Redding GJ, Everard ML. Chronic wet cough: protracted bronchitis, chronic suppurative lung disease and bronchiectasis. Pediatr Pulmonol. (2008) 43:519–31. 10.1002/ppul.20821
Karimdjanov I.A., Zokirova U.I., Yusupova G.A., Karimova U.N. The role of association of ADRB2 gene polymorphism with therapeutic response to β2-agonists in children with recurrent bronchial obstruction. Child’s Health. (2022)17(2);19-23.
Chang AB, Upham JW, Masters IB, Redding GR, Gibson PG, Marchant JM, et al.. Protracted bacterial bronchitis: the last decade and the road ahead. Pediatr Pulmonol. (2016) 51:225–42 10.1002/ppul.23351
Chang AB, Robertson CF, Van Asperen PP, Glasgow NJ, Mellis CM, Masters IB, et al.. A multicenter study on chronic cough in children: burden and etiologies based on a standardized management pathway. Chest. (2012) 142:943–50. 10.1378/chest.11-2725
Gedik AH, Cakir E, Torun E, Demir AD, Kucukkoc M, Erenberk U, et al.. Evaluation of 563 children with chronic cough accompanied by a new clinical algorithm. Ital J Pediatr. (2015) 41:73. 10.1186/s13052-015-0180-0
Wurzel DF, Marchant JM, Yerkovich ST, Upham JW, Mackay IM, Masters IB, et al.. Prospective characterization of protracted bacterial bronchitis in children. Chest. (2014) 145:1271–8. 10.1378/chest.13-2442 [
Stämpfli MR, Anderson GP. How cigarette smoke skews immune responses to promote infection, lung disease and cancer. Nat Rev Immunol. (2009) 9:377–84. 10.1038/nri2530
Marchant JM, Masters IB, Taylor SM, Chang AB. Utility of signs and symptoms of chronic cough in predicting specific cause in children. Thorax. (2006) 61:694–8. 10.1136/thx.2005.056986
Di Filippo P, Scaparrotta A, Petrosino M, Attanasi M, Di Pillo S, Chiarelli F, et al.. An underestimated cause of chronic cough: the protracted bacterial bronchitis. Ann Thorac Med. (2018) 13:7. 10.4103/atm.ATM_12_17
de Blic J, Midulla F, Barbato A, Clement A, Dab I, Eber E, et al.. Bronchoalveolar lavage in children. Eur Respir J. (2000) 15:217–31. 10.1183/09031936.00.15121700
Pohunek P, Pokorná H, StríŽ I. Comparison of cell profiles in separately evaluated fractions of bronchoalveolar lavage (BAL) fluid in children. Thorax. (1996) 51:615–8. 10.1136/thx.51.6.615 [
Verhulst S, Boel L, van Hoorenbeeck K. Protracted bacterial bronchitis: bronchial aspirate versus bronchoalveolar lavage findings: a single-centre retrospective study. BMJ Paediatr Open. (2019) 3:e000507. 10.1136/bmjpo-2019-000507
Wurzel DF, Marchant JM, Clark JE, Masters IB, Yerkovich ST, Upham JW, et al.. Wet cough in children: Infective and inflammatory characteristics in broncho-alveolar lavage fluid. Pediatr Pulmonol. (2014) 49:561–8. 10.1002/ppul.22792
Donnelly D, Critchlow A, Everard ML. Outcomes in children treated for persistent bacterial bronchitis. Thorax. (2007) 62:80–4. 10.1136/thx.2006.058933
van Der Gast CJ, Cuthbertson L, Rogers GB, Pope C, Marsh RL, Redding GJ, et al.. Three clinically distinct chronic pediatric airway infections share a common core microbiota. Ann Am Thorac Soc. (2014) 11:1039–48. 10.1513/AnnalsATS.201312-456OC
Marsh RL, Kaestli M, Chang AB, Binks MJ, Pope CE, Hoffman LR, et al.. The microbiota in bronchoalveolar lavage from young children with chronic lung disease includes taxa present in both the oropharynx and nasopharynx. Microbiome. (2016) 4:37. 10.1186/s40168-016-0182-1
Cuthbertson L, Craven V, Bingle L, Cookson WOCM, Everard ML, Moffatt MF. The impact of persistent bacterial bronchitis on the pulmonary microbiome of children. PLoS ONE. (2017) 12:e190075. 10.1371/journal.pone.0190075
Marsh RL, Smith-Vaughan HC, Chen ACH, Marchant JM, Yerkovich ST, Gibson PG, et al.. Multiple respiratory microbiota profiles are associated with lower airway inflammation in children with protracted bacterial bronchitis. Chest. (2019) 155:778–86. 10.1016/j.chest.2019.01.002
Marchant J, Masters IB, Champion A, Petsky H, Chang AB. Randomised controlled trial of amoxycillin clavulanate in children with chronic wet cough. Thorax. (2012) 67:689–93. 10.1136/thoraxjnl-2011-201506 [